US are falling after the Federal Reserve said it plans to buy $US600 billion ($601.93 billion) in Treasurys to stimulate the US economy.
Investors had been waiting throughout the day to see exactly how big the bond-buying program would be. The Fed's aim is to drive interest rates lower in an effort to spark spending and lending.
The spending program falls largely inline with analysts' expectations.
Stocks had been rallying over the past two months, in part, due to growing expectations the Fed would provide a lift to the sluggish economy.
The Dow Jones industrial average is down 66, or 0.6 per cent, at 11,124. The S&P 500 is down 7, or 0.6 per cent, at 1186, while the Nasdaq composite is down 18, or 0.7 per cent, at 2516.
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